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Key Differences

VSL#3® is a refrigerated, high-potency probiotic medical food intended for the dietary management of IBS, ulcerative colitis, and pouchitis. It is the #1 gastroenterologist-recommended multi-strain probiotics brand.

VSL4 Gut is a shelf-stable probiotic supplement scientifically formulated to support regularity and healthy digestion.*

VSL#3®

Intended for the dietary management of IBS, UC, and pouchitis

VSL4 Gut

Promotes regularity and healthy digestion*

The #1 gastroenterologist-recommended multi-strain probiotics brand
From the makers of VSL#3®
Eight complementary strains from three different genera
Features the same eight strains as VSL#3®
Highest-Potencies (112.5B to 900B CFU)
Potent (30B CFU)
Refrigerated
Shelf-stable
Probiotic Medical Food
Probiotic Supplement

VSL#3®

Intended for the dietary management of IBS, UC, and pouchitis

The #1 gastroenterologist-recommended multi-strain probiotics brand
Eight complementary strains from three different genera
Highest-Potencies (112.5B to 900B CFU)
Refrigerated
Probiotic Medical Food

VSL4 Gut

Promotes regularity and healthy digestion*

From the makers of VSL#3®
Features the same eight strains as VSL#3®
Potent (30B CFU)
Shelf-stable
Probiotic Supplement

A diverse gut microbiome may lead to better gut health.*

While VSL#3® and VSL4 Gut are intended for different purposes, they both feature the same well-researched eight strains.